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Webinar Featuring Karthik Suresh

Webinar Featuring Karthik Suresh

Thursday, January 6, 2022 (1:00 PM - 2:00 PM) (EST)


"Mitochondrial ROS-induced Ca2+ influx and microvascular endothelial cell dysfunction in pulmonary arterial hypertension (PAH)" will feather Dr. Karthik Suresh, Assistant Professor of Medicine, Johns Hopkins Medical Institute 

Dr. Karthik Suresh is a pulmonary and critical care physician. His clinical interests include acute lung injury and critical care medicine. He also specializes in the diagnosis and management of immune-related lung injury, especially in the context of autoimmune conditions and chemotherapy/immunotherapy for cancer.

Dr. Suresh is a member of the Hopkins immune-related adverse events (irAE) tox team. He also takes care of critically ill patients in the medical and oncology ICUs. He’s a firm faculty member for the Janeway Firm of the Osler Housestaff Medical Service and provides teaching to medical students, housestaff and fellows.


Pulmonary arterial hypertension (PAH) is a highly morbid disease characterized by high pulmonary arterial pressures, leading to right ventricular failure and death. Complex, vaso-occlusive lesions in the lung microvasculature are thought to contribute to increased pulmonary vascular pressures in this disease. These lesions are composed of several cell types, including lung microvascular endothelial cells (MVECs). Our lab has focused on mechanisms by which lung MVECs acquire pseudo-oncogenic characteristics (such as increased migration and proliferation) which are thought to drive formation of vaso-occlusive lesions in the lung microvasculature. Specifically, I will discuss our work on how mitochondrial dysfunction and increased intracellular calcium levels may be playing a role in promoting abnormal MVEC function in PAH.


All members in good standing of NAVBO can attend this webinar at no cost.  Non-members can attend for a $25 fee (consider joining to reap all of the benefits of NAVBO)

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Bernadette Englert
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Thursday, January 6, 2022 (1:00 PM - 2:00 PM) (EST)
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