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DTSTART;TZID=America/New_York:20250909T000000
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SUMMARY:Recorded Webinar Featuring Stephan Huveneers\, Ph.D.
DESCRIPTION:Our next webinar will be with Dr. Stephan Huveneers\, Associate Professor from University Medical Center in Amsterdam. The title of his talk is "Force-dependent regulation of endothelial adhesion in vascular development and disease." Abstract: Blood vessels are continuously exposed to mechanical forces such as shear stress\, blood pressure\, and vessel wall stiffness. The vascular endothelium a dynamic barrier between blood and tissue plays a critical role in sensing these mechanical cues through a process known as mechanotransduction. This process is essential for maintaining vascular homeostasis\, and its dysregulation contributes to stiffness-associated cardiovascular diseases\, including hypertension\, edema\, and atherosclerosis. A key determinant of endothelial function lies in the force-sensitive nature of cell adhesions\, particularly integrin-based adhesions and intercellular junctions. In our work\, we investigate how these adhesive structures respond and adapt to mechanical forces. I will present our latest findings identifying novel molecular systems that regulate endothelial barrier function and angiogenesis.
X-ALT-DESC;FMTTYPE=text/html:Our next webinar will be with Dr. Stephan Huveneers\, Associate Professor from University Medical Center in Amsterdam. The title of his talk is "\;Force-dependent regulation of endothelial adhesion in vascular development and disease."\; \;
Abstract: Blood vessels are continuously exposed to mechanical forces such as shear stress\, blood pressure\, and vessel wall stiffness. The vascular endothelium&mdash\;a dynamic barrier between blood and tissue&mdash\;plays a critical role in sensing these mechanical cues through a process known as mechanotransduction. This process is essential for maintaining vascular homeostasis\, and its dysregulation contributes to stiffness-associated cardiovascular diseases\, including hypertension\, edema\, and atherosclerosis. A key determinant of endothelial function lies in the force-sensitive nature of cell adhesions\, particularly integrin-based adhesions and intercellular junctions. In our work\, we investigate how these adhesive structures respond and adapt to mechanical forces. I will present our latest findings identifying novel molecular systems that regulate endothelial barrier function and angiogenesis.
LOCATION:
UID:e.2142.1268072
SEQUENCE:3
DTSTAMP:20260430T110539Z
URL:https://members.navbo.org/calendar-of-events/Details/recorded-webinar-featuring-stephan-huveneers-ph-d-1484782?sourceTypeId=Hub
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