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March 2024

Calll for Nominations - Deadline Tomorrow!

Remembering David Dichek

Fundamental Papers

The NAVBO Education Committee requests your assistance in maintaining our listing of Fundamental Papers in Vascular Biology found on our web site.

This is a valuable resource for trainees and others who visit our site. Periodically these listings are updated, and it is now time to repeat this process. If you are supervising trainees or currently teaching vascular biology and related courses, whether graduate or undergraduate, please complete the form at this link to recommend papers you think should be included in our list. Please complete a new form for each paper you suggest.

New Group for Early-Stage Investigators

Attention: Senior postdocs looking for a faculty position, and junior faculty who have recently started their own labs 

NAVBO is happy to announce the formation of a forum for early-stage investigators (ESIs) who are looking to, or have recently transitioned to independent faculty positions. This forum will serve as a place where NAVBO members who are ESIs can share their questions and experiences about the entire process , and receive feedback from their peers, and also senior faculty. The forum will additionally hold in-person events at the annual Vascular Biology meetings, featuring faculty at various levels in their careers  who will share their personal experiences and answer questions from the audience. We jumpstarted this forum earlier this week with a well-attended and lively “Mentoring Early-Stage Investigators” event organized by the NAVBO Diversity, Equity and Inclusion (DEI) Committee, featuring David Gordon, MD. 

To Join: Go to the NAVBO Member Portal, from the left menu, select My Subscriptions, then select Early-Stage Investigators.  Please note: This group is limited to current NAVBO members only.

Lab of the Month

Did You Know?

Did you know that there is a NAVBO Member App?

Download the Member Plus app from the Apple or Android/Google app store. Sign in with your NAVBO log in.  Easily access your profile and billing info, the NAVBO directories - Current Members and Corporate Members, see and register for upcoming events, and view and participate in the Vascular Network Forum

"Did You Know?" is provided by the NAVBO Membership Committee

IVBM 2024 -  Register Soon

Early Bird Deadline is April 1

Special thanks to all the NAVBO members who volunteered to review abstracts!!

Travel Awards to the IVBM 2024

NAVBO is sponsoring up to eight $1,000USD Travel Awards for its trainee members (students or postdocs). You must have submitted an abstract to the IVBM (deadline was February 20) and your application for the travel award must be submitted by April 1, 2024.  The NAVBO Meritorious Awards Committee will review the applications and select up to eight recipients.  To apply, complete this form. Be sure to have all necessary documents in pdf format - see our web site for more details.

Spotlight on Trainees

Increased use of childcare cost support policy by NRSA fellows in FY 2023

Family support at critical periods can be crucial for professional development, especially for female and underrepresented scientists, providing sound rationale for NIH’s family-friendly policies aimed early-career researchers. One such policy up to $2,500 in childcare cost support to full-time NRSA fellows and trainees. Childcare cost support may be requested as part of a new NRSA application, a continuing application, or as an administrative supplement made during the fellowship period. NIH reports that the percentage of fellows that received childcare cost support rose from 5.6% in FY 2021 to 8.4% in FY 2023, driven by a greater than 40% increase in total number of childcare awards from FY 2021 to FY 2023.

Member News

Welcome to our New Members:

Marianna Barbuto, University of Pittsburgh

Ricardo Bernardino de Paula, University of South Carolina

Pauline Bougaran, UNC Chapel Hill

Samantha Chaney, University of South Alabama

Ygor Marinho Ferreira Dos Santos, 

Sojin Kim, Icahn School of Medicine

Girija Konduri, Medical College of Wisconsin

Hanyu Liu, University of Oxford

Aparna Mahadevan, Nanyang Technological University

Huize Pan, Vanderbilt University Medical Center

Antonio Queiro-Palou, Karolinska Institutet

Meghan Riddell, University of Alberta

Jose Rodriguez Renteria, Universidad Autonoma de San Luis Potosi
Maria Serrano, Boston University

Apeksha Shapeti, KU Leuven

Taha Kadir Yesin, Ege University Faculty of Medicine/Oxford University Radcliffe Department of Medicine

NAVBO Meetings and Events

Keep up to date on NAVBO happenings through the Calendar of Events

Click on the image to go to the web page.

Vasculata 2024 - Registration Open!!

Vasculata 2024 - July 22-25, 2024 at Stanford University

Registration for Vasculata 2024 is now open.  You can also submit at abstract and/or apply for a need-based scholarship.  Each day will cover a main theme - 

Monday, July 22: Basic Vascular Biology and Recent Innovations
Tuesday, July 23: Vascular Diseases and Disease Models
Wednesday, July 24: From Biology to Therapy (Translational Research)

Thursday, July 25: Turning Promising Research Ideas into Clinical Applications

Recent Member Publications

Caveolin-1 mediates blood-brain barrier permeability, neuroinflammation, and cognitive impairment in SARS-CoV-2 infection

Journal of Neuroimmunology

Blood-brain barrier (BBB) permeability can cause neuroinflammation and cognitive impairment. Caveolin-1 (Cav-1) critically regulates BBB permeability, but its influence on the BBB and consequent neurological outcomes in respiratory viral infections is unknown.  Read More

Engineered Wnt7a ligands rescue blood-brain barrier and cognitive deficits in a COVID-19 mouse model

Brain

Respiratory infection with SARS-CoV-2 causes systemic vascular inflammation and cognitive impairment. We sought to identify the underlying mechanisms mediating cerebrovascular dysfunction and inflammation following mild respiratory SARS-CoV-2 infection. To this end, we conduced unbiased transcriptional analysis to identify brain endothelial cell signaling pathways dysregulated by mouse adapted SARS-CoV-2 MA10 in aged immunocompetent C57Bl/6 mice in vivo.  Read More

Functional, Structural and Proteomic Effects of Ageing in Resistance Arteries

International Journal of Molecular Sciences

The normal ageing process affects resistance arteries, leading to various functional and structural changes. Systolic hypertension is a common occurrence in human ageing, and it is associated with large artery stiffening, heightened pulsatility, small artery remodeling, and damage to critical microvascular structures.  Read More

Mechanosensitive super-enhancers regulate genes linked to atherosclerosis in endothelial cells

Journal of Cell Biology

Vascular homeostasis and pathophysiology are tightly regulated by mechanical forces generated by hemodynamics. Vascular disorders such as atherosclerotic diseases largely occur at curvatures and bifurcations where disturbed blood flow activates endothelial cells while unidirectional flow at the straight part of vessels promotes endothelial health. Read More

Pediatric sepsis inflammatory blood biomarkers that correlate with clinical variables and severity of illness scores

Journal of Inflammation

Sepsis is a dysregulated systemic inflammatory response triggered by infection, resulting in organ dysfunction. A major challenge in clinical pediatrics is to identify sepsis early and then quickly intervene to reduce morbidity and mortality. As blood biomarkers hold promise as early sepsis diagnostic tools, we aimed to measure a large number of blood inflammatory biomarkers from pediatric sepsis patients to determine their predictive ability, as well as their correlations with clinical variables and illness severity scores. Read More

If you recently published a paper and would like to have it included in a future issue of the NAVBO NewsBEAT and/or on our web site.  Please send the citation to membership@navbo.org

Special Thanks to Vascular Biology 2023 Supporters

Industry News

AHA resources for patient education on cardiovascular effects of SARS-CoV-2 infection

 The American Heart Association has made available a suite of digital materials, including some for continuing education credit, to facilitate the rapid education of outpatients on potential cardiovascular effects accompanying COVID-19. Since angiotensin converting enzyme 2 (ACE2), the putative receptor for CoV-2 is widely expressed in the cardiovascular system, damage to the heart and lungs can occur. Thus it is important to familiarize healthcare professionals with the latest progress on phenotypes and mechanisms of COVID-19-related systemic injuries, better informing therapeutic planning.

 NOMIS & Science Young Explorer Award open for applications

 Researcher working at the intersection of the social and life sciences are encouraged to apply for the NOMIS & Science Young Explorer Award, recognizing early-career M.D., Ph.D., or M.D./Ph.D. scientists. Essays submitted in application are judged for clarity, scientific quality, creativity, and demonstration of cross-disciplinary approaches to address fundamental questions. A cash prize of up to US $15,000 will be awarded to essay winners, and their engaging essays will be published in Science. Winners will also be invited to share their work and forward-looking perspective with leading scientists in their respective fields at an award ceremony. Information on applications (due May 15, 2024) may be found at www.science.org/nomis.

Navigational advances in cerebral vessel catheterization

 Dreyfus et al., writing in Science Robotics, describe use of a highly dexterous, magnetically steered articulated robot to improve dynamic catheterization in tortuous blood vessels, often encountered in efforts to revascularize during acute ischemic stroke. The complex networked arrangement of blood vessels in the brain continues to pose a challenge for access and resolution of thrombi associated with stroke. The device described successfully guided endovascular navigation from the aorta to millimeter-sized cranial arteries in vivo, demonstrating its potential utility for accessing occluded vessels in the brain.

NAVBO Corporate Partners

NAVBO Corporate Members

Summer Programs

PRIDE CVD-CGE
Cardiovascular Disease Comorbidities, Genetics and Epidemiology

June 21-27, 2024 (Virtual 10am - 3pm CT)
July 7 -13, 2024 (In Person)
7/22, 7/24, 7/26, 8/5, 8/7, & 8/9 (Virtual 10am - 2pm CT)
Dates and Times subject to change

“PRIDE mentorship provided the foundation to build my work, allowed me to think outside the box, and provided an opportunity to build lasting collaborations with PRIDE cohorts and mentors, and to jointly publish and write grants. PRIDE provides an amazingly enriching experience and I strongly recommend it.”  –  PRIDE Mentee, 2008

This NHLBI-funded “Programs for Inclusion and Diversity Among Individuals Engaged in Health-Related Research” support junior faculty underrepresented in biomedical research. 

Washington University School of Medicine, St. Louis, Missouri

MPI’s:  Victor Davila-Roman, MD, Lisa de las Fuentes, MD, MS and DC Rao, PhD

Program Administrator:  Linda Schreier, BS (schreierl@wustl.edu)

Space is limited for the mentored program starting summer 2024.  Apply early!

Calls for Papers/Proposals

Calendar of Events

Job Postings

North American Vascular Biology Organization
18501 Kingshill Road
Germantown, MD 20874-2211
(301) 760-7745
info@navbo.org