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July 2024 |
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Meet our New President Elect - Wayne Orr |
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Congratulations Dr. Wayne Orr - President Elect Dr. Wayne Orr grew up in Arkansas and received his PhD in 2002 from the University of Alabama at Birmingham, working on thrombospondin-dependent regulation of endothelial cell function with Dr. Joanne Murphy-Ullrich. With an interest in extracellular matrix-driven signaling responses, Dr. Orr took a postdoctoral fellowship in Dr. Martin Schwartz’s laboratory in the Cardiovascular Research Center at the University of Virginia. His postdoctoral work examined the intersection between matrix composition and mechanical forces in the regulation of endothelial function in early atherosclerosis. In addition, collaborations with Drs. Briam Wamhoff and Gary Owens sparked Dr. Orr’s interest in the regulation of smooth muscle function by matrix composition and adhesion signaling. |
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faculty position at LSU Health Shreveport in 2007. At LSU, Dr. Orr’s laboratory has focused on signaling by the integrin family of matrix receptors in endothelial cell phenotype in atherosclerosis, with a particular interest in the role of the Nck adaptor proteins in atherogenic endothelial activation. In addition, Dr. Orr has established a research program in signaling by the “neuronal guidance molecule” family of cell adhesion receptors, showing a particularly important role for the receptor EphA2 in both atherogenic inflammation and smooth muscle fibroproliferative remodeling. In 2017, Dr. Orr took over as Director of the Center for Cardiovascular Diseases and Sciences (CCDS) at LSU Health Shreveport. |
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Abstract Submission Deadline is August 1!! |
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Join us for Vascular Biology 2024!! October 20-24, 2024 at the Asilomar Conference Grounds in Monterey |
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Submit your abstract to Vascular Biology 2024 by August 1! Opportunities to present abound! We will program 50 abstracts as short talks into our main sessions, 15 Nano Talks, an addtional 6 short talks in the Pre-Conference Meeting for Trainees, and over 150 posters! Be sure to submit your abstract soon!
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Vascular Biology 2024 will be cover the themes of Development and Genetics, Inflammation, Marix Biology and Bioengineering, Signaling and Microcirculation, with an additional general session on Vascular Malformations, co-sponsored by the Sturge-Weber Foundation, and a session on HHT sponsored by Cure HHT. The Microcirculatory Society is once again joining us and sponsoring several sessions including, Microvascular Changes During Pregnancy, which is the MCS President's symposium organized by Pooneh Bagher.
We are super excited to welcome Dr. William Sessa, Senior Vice President and Chief Scientific Officer, Pfizer Inc., as our Keynote Speaker. His lecture is entitled, Endothelium at the interface of lipid metabolism and vascular function. We will then end the meeting with more on Metabolism, a session featuring Drs. Joseph Loscalzo, Brigham and Women’s Hospital; Dionna Kasper, Dartmouth College; Yajaira Suarez, Yale School of Medicine; and Kristen Zuloaga, Albany Medical College. Plan to stay through the end - Thursday, October 24 at 1:00pm.
In addition to our outstanding scientific sessions, we are sponsoring the Pre-conference Meeting for Trainees, two workshops on DEI, and two career development sessions. We'll have Nano-Talks, three nights of Poster Sessions with poster discussions lead by postdocs, and we're bring back our Networking 101 session for those new to the meeting and/or NAVBO.
Registration is open and we are accepting abstracts. Travel Awards are available for NAVBO and MCS trainee members, more information is available on our web site.
Early Bird Deadline - August 31, 2024
The full program is on our web site - https://navbo.org/vb2024 |
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Special Thanks to Vascular Biology 2024 Supporters |
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Call for Proposals for Lymphatic Forum 2027 |
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Are you interested in organizing the 2027 Lymphatic Forum?
NAVBO and the Lymphatic Education & Research Network (LE&RN) invite institutions of higher learning to apply to host the Lymphatic Forum 2027,
The Lymphatic Forum is intended to bring together a diverse group of scientists and clinicians studying different aspects of normal and pathological lymphatic biology using different experimental models. This meeting is intended to provide a unique format for the exchange of ideas and information, to evaluate the current views on the functional roles of the lymphatic vasculature in health and disease, and to attract early investigators, young postdocs and students to join this expanding research area.
This biennial meeting was inaugurated in 2013 at Yale University (New Haven, CT), and has since been sponsored by the National Institutes of Health (NIH, 2015), Northwestern University (Chicago, IL, 2017), Texas A&M University (Austin, TX 2019), Virtual conference (2021), University of Calgary (Banff, Alberta, Canada, 2023), and Northwestern University (Chicago, IL 2025).
Institutions interested in hosting the forum in 2027 are invited to submit a proposal . All applications will be considered on their merit alignment with the Forum’s ambitious goals. Proposal due date: September 15, 2024
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Lab of the Month |
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Month - July 2024 The Lab of Dr. Taija Mäkinen This month we are highlighting the lab of Dr. Taija Mäkinen, Professor at Uppsala University and Wihuri Research Institute/University of Helsinki. Find out more about her lab by visiting her page in our Lab of the Month listing. |
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Open Survey for Researchers |
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Are you a researcher planning to attend scientific conferences? Please consider participating in and distributing this survey on researchers’ expectations of conferences that Ariane Wenger – a doctoral student at the Transdisciplinarity Lab (TdLab), ETH Zurich – is conducting as part of her dissertation on changing research exchange practices. The short (10 minutes) online survey is aimed at researchers of all scientific disciplines and career stages who are planning to attend scientific conferences. In particular, opinions and views of researchers from all around the world are appreciated. Participation in the survey will not only enrich this study, but will also help to identify avenues for enhancing current conference practices, benefiting the wider academic community. The survey can be accessed here: https://ww3.unipark.de/uc/cexp1/. Thank you very much for your contribution! |
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Spotlight on Trainees |
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NPA workshop series extends into the late summer and fall The National Postdoctoral Association is well into its third year of offering a series of workshops fostering development of crucial professional skills for trainees at the postdoctoral level. Courses in the SmartSkills series are free to postdocs who are members of the NPA. Courses remining for 2024 include Perfecting Presentation Skills (August 27), Advocating for Public Policy (September 24), Grantwriting (October 22), and Understanding Research Development Careers (November 19). |
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Member News |
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Welcome to our New Members: Audra Barnes, Virginia Tech Ramon Bossardi Ramos, Albany Medical College Ying Deng, Montreal Clinical Research Institute Xuebin Fu, Northwestern University Zheng Jing, University of California, Los Angeles Minsoo Kim, University of Pennsylvania Anna Kolarzyk, Cornell University Rajeev Malhotra, Harvard Medical School Nina Martino, Albany Medical Health System Shafeeque Mohammedali, UTH Health Houston Tasneem Mustafa, University of California, Irvine Brooke O'Donnell, University of Virginia Meleah Pea, LSU Health Shreveport Sydney Rudolph, Wayne State University Xinyi Sun, Johns Hopkins University Can Tan, Northwestern University Qi Tan, Oxford University Aleksandra Tata, Duke University Kanika Verma, LSU Health Shreveport Qianxun Wang, UIC College of Medicine Xiaosong Wang, Novartis Yuheng Zhang, University of Oxford Yunpei Zhang, Oregon Health & Science University Bisheng Zhou, University of Illinois at Chicago |
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Recent Member Publications |
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Heterogeneous gene expression during early arteriovenous fistula remodeling suggests that downregulation of metabolism predicts adaptive venous remodeling Scientific Reports Clinical outcomes of arteriovenous fistulae (AVF) for hemodialysis remain inadequate since biological mechanisms of AVF maturation and failure are still poorly understood. Aortocaval fistula creation (AVF group) or a sham operation (sham group) was performed in C57BL/6 mice. Read More
Disturbed flow in the juxta-anastomotic area of an arteriovenous fistula correlates with endothelial loss, acute thrombus formation, and neointimal hyperplasia American Journal of Physiology-Heart and Circulatory Physiology Clinical failure of arteriovenous neointimal hyperplasia (NIH) fistulae (AVF) is frequently due to juxta-anastomotic NIH (JANIH). Although the mouse AVF model recapitulates human AVF maturation, previous studies focused on the outflow vein distal to the anastomosis. Read More
Sepsis induces heterogeneous transcription of coagulation- and inflammation-associated genes in renal microvasculature Thrombosis Research Background: Acute kidney injury (AKI) in sepsis patients increases patient mortality. Endothelial cells are important players in the pathophysiology of sepsis-associated AKI (SA-AKI), yet knowledge regarding their spatiotemporal involvement in coagulation disbalance and leukocyte recruitment is lacking. This study investigated the identity and kinetics of responses of different microvascular compartments in kidney cortex in response to SA-AKI. Read More
Modulation of angiopoietin-2 and Tie2: Organ specific effects of microvascular leakage and edema in mice Microvascular Research Critical illness is associated with organ failure, in which endothelial hyperpermeability and tissue edema play a major role. The endothelial angiopoietin/Tie2 system, a regulator of endothelial permeability, is dysbalanced during critical illness. Elevated circulating angiopoietin-2 and decreased Tie2 receptor levels are reported, but it remains unclear whether they cause edema independent of other critical illness-associated alterations. Read More
mTORC1 Signaling in Brain Endothelial Progenitors Contributes to CCM Pathogenesis Circulation Research Background: Cerebral vascular malformations (CCMs) are primarily found within the brain, where they result in increased risk for stroke, seizures, and focal neurological deficits. The unique feature of the brain vasculature is the blood-brain barrier formed by the brain neurovascular unit. Recent studies suggest that loss of CCM genes causes disruptions of blood-brain barrier integrity as the inciting events for CCM development. Read More
If you recently published a paper and would like to have it included in a future issue of the NAVBO NewsBEAT and/or on our web site. Please send the citation to membership@navbo.org |
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Industry News |
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NASEM releases expert assessment of Long COVID’s defining features The lack of a clear definition for Long COVID has presented major challenges for policymakers, health professionals, and patients. The National Academies of Sciences, Engineering, and Medicine, tasked with querying experts and producing such a consensus definition, has issued a report, titled A Long COVID Definition: A Chronic, Systemic Disease State with Profound Consequences (2024), that captures the state of current understanding based on existing literature and input from stakeholders and patients.
Input sought on draft NIH Public Access Policy In 2022, the Biden Administration directed federal agencies to update policies and establish transparent procedures to accelerate access of the public to findings from federally-funded research. Accordingly, the NIH has released a draft of its updated Public Access Policy in support of its obligation to advance access to NIH-funded research results. Public comments on the Draft Public Access Policy will be accepted until August 19, 2024, and can be submitted through the comment portal found here.
AAMC to offer virtual workshop on managing workplace conflict Some degree of conflict is to be expected in any work environment, and successful navigation through conflict is key to maintaining fruitful relationships and building trust with collaborators. The American Association of Medical Colleges has announced upcoming dates for its Transforming Conflict into Collaboration Virtual Workshop, which seeks to expand participants’ conflict management skills, self-awareness, and communication chops in thorny situations. Registration is now open for workshop dates in September and December. |
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NAVBO Corporate Partners |
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NAVBO Corporate Members |
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Summer Programs |
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PRIDE CVD-CGE June 21-27, 2024 (Virtual 10am - 3pm CT)
“PRIDE mentorship provided the foundation to build my work, allowed me to think outside the box, and provided an opportunity to build lasting collaborations with PRIDE cohorts and mentors, and to jointly publish and write grants. PRIDE provides an amazingly enriching experience and I strongly recommend it.” – PRIDE Mentee, 2008 |
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This NHLBI-funded “Programs for Inclusion and Diversity Among Individuals Engaged in Health-Related Research” support junior faculty underrepresented in biomedical research.
Washington University School of Medicine, St. Louis, Missouri MPI’s: Victor Davila-Roman, MD, Lisa de las Fuentes, MD, MS and DC Rao, PhD Program Administrator: Linda Schreier, BS (schreierl@wustl.edu)
Space is limited for the mentored program starting summer 2024. Apply early! |
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Calendar of Events |
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Job Postings |
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North American Vascular Biology Organization |