Description

Join us for our webinar with Walter Lee Murphy, Ph. D., J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville. The title of his talk is "Re-Discovering Angiogenesis and Lymphangiogenesis Through Computational, In Vitro and In Vivo Views."

Abstract: Understanding angiogenesis, similar to other physiological processes, requires identifying multiple cell, system, and environmental interactions. A challenge is identifying these dynamics when you cannot observe them using traditional experimental approaches. Fundamental questions still remain unanswered. What cells are involved? Where do cells come from? Where do cells go? This presentation will highlight the impact of biomimetic model development for making new discoveries about the cellular dynamics involved in adult microvascular network remodelling and the growth of new blood vessels. Novel observations made possible by computational modelling of shear stresses along sprouts and time-lapse imaging of intact cultured tissues motivate new paradigms related to the roles for shear stress, lymphatic-blood vessel plasticity, and the vasculogenic potential for stem cell populations. Altogether the presentation will serve to frame an appreciation for how new “views” can encourage vascular biologists and physiologists to rethink what we know about angiogenesis.